By Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Lyla M. Hernandez
Till rather lately, genetic details was once used basically within the analysis of quite infrequent genetic illnesses, akin to cystic fibrosis and Huntington's sickness, yet a metamorphosis within the use of genetic and genomic details is underway. whereas many predictions were made that genomics will rework drugs, so far few of those promising discoveries have ended in real purposes in medication and health.The Institute of Medicine's around desk on Translating Genomic-Based study for healthiness, tested in 2007, held its first workshop to deal with the next questions: are there various pathways through which new medical findings stream from the learn atmosphere into future health care? if that is so, what are the results of these diversified pathways for genomics? What will we research from the interpretation of different new applied sciences as we search to appreciate the interpretation of genome technological know-how into well-being care? info got from the workshop was once then used to additional dialogue and exploration of the solutions to those questions. This e-book summarizes speaker shows and discussions. Any conclusions mentioned shouldn't be construed as reflecting a gaggle consensus; quite they're the statements and critiques of presenters and individuals.
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Additional info for Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary
This, in turn, raises concerns about equity—for example, about lack of access to these technologies for those who do not have the means to pay. Another issue concerns the diffusion of tests that would identify predispositions to future disease for which there are no cures, only treatments with limited effectiveness and major side effects. Patients may vary greatly in their decisions about whether to have the genetic test for Huntington’s Disease, for example. Diffusion processes are fundamentally affected by patient preferences and by the public’s perception of the value of health-risk information.
Copyright © National Academy of Sciences. All rights reserved. D. Moderator A member of the audience commented that she believed Gelijns overestimated the use and the effect of cost-effectiveness analysis (CEA) in insurance decisions. The United Kingdom, she said, has adopted CEA and uses it for health-policy decisions, including those made by the National Health Service, but there is no mechanism in the United States for such analysis, and there is no systematic application of a quality threshold.
It can be characterized as a learning process, and a fundamental aspect of learning is the reduction of uncertainty. Downstream learning can lead to changes in a technology or to refinements in its use. At the same time it poses new questions for basic and translational research and thereby enriches the ultimate payoff. The determinants of diffusion in genomics are probably very similar to those for other medical technologies. Diffusion depends not only on the benefits that a new intervention provides, but also, importantly, on the institutional environment in which a technology is imbedded.