By Janet E. Murphy, David P. Ryan (auth.), Peter Mueller, Andreas Adam (eds.)
Interventional Oncology is a fast-growing new box, in addition to an rising forte. Many minimally-invasive, imaging-guided tactics look set to interchange extra conventional open surgical recommendations of treating stable tumors in various organs. the purpose of this booklet is to explain new interventional radiological tools in a succinct and sensible shape. Diagnostic radiological concerns correct to the choice and follow-up of sufferers also are lined. The booklet starts with an summary of the fundamental ideas of present interventional suggestions, together with thermal ablation, excessive depth centred ultrasound, and embolization. Later chapters specialize in tumors of the liver, kidney, lung, and bone, putting new interventional recommendations in context through concerning the surgical and oncologic tools of treating an analogous stipulations. With an emphasis on top practices, Interventional Oncology: a pragmatic advisor for the Interventional Radiologist will function a definitive advisor to training physicians considering this swiftly evolving field.
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Extra resources for Interventional Oncology: A Practical Guide for the Interventional Radiologist
Example text
Am J Surg. 2008;195:775–81. 11. Dodd 3rd GD, Frank MS, Aribandi M, Chopra S, Chintapalli KN. Radiofrequency thermal ablation: computer analysis of the size of the thermal injury created by overlapping ablations. AJR Am J Roentgenol. 2001;177:777–82. 12. Gervais DA, McGovern FJ, Arellano RS, McDougal WS, Mueller PR. Radiofrequency ablation of renal cell carcinoma: part 1, Indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. AJR Am J Roentgenol. 2005;185:64–71.
For example, very poor tumor thermal conductivity limits heat transmission centrifugally away from the electrode with marked heating in the central portion of the tumor, and limited, potentially incomplete heating in peripheral portions of the tumor. , heat dissipation) with potentially incomplete and heterogeneous tumor heating. Furthermore, in recent agar phantom and computer modeling studies, Liu et al. demonstrated that differences in thermal conductivity between the tumor and surrounding background tissue (specifically, decreased thermal conductivity from increased fat content of surrounding tissue) result in increased temperatures at the tumor margin.
Marked tumor vascularity (such as is seen in HCC) limits RF tissue heating, and so optimal treatment likely includes performing adjuvant TACE first or administering adjuvant antiangiogenic therapy. (b) Size and number of tumors. 5 cm) requiring combination therapy. , RF ablation for the primary tumor and TACE for the residual peripheral satellite nodules). (c) Accessibility and visibility. , can it be easily seen and reached via a percutaneous approach) should also factor into any decision on combination therapy.