By Christopher P. Cannon
During this moment version of his hugely acclaimed publication, Christopher P. Cannon, MD, and a crew of preeminent medical investigators have completely revised and accelerated each bankruptcy to mirror the new explosion of scientific trials at the administration of acute coronary syndromes (ACS). This comprises: the more moderen assessments, equivalent to C reactive protein; a multimarker method of analysis and danger stratification; new antiplatelet brokers; and mixtures of thrombolytic-antithrombotic regimens. additionally mentioned are the most recent advancements in interventional cardiology, using cost-effectiveness in medical trials to settle on acceptable treatments, and the employment of severe pathways research to enhance compliance with evidence-based medication and guide techniques.
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Extra info for Management of Acute Coronary Syndromes (Contemporary Cardiology)
Example text
J Am Coll Cardiol 1994:13A. 91. Braunwald E. The open-artery theory is alive and well—again. N Engl J Med 1993;329:1650–1652. 92. Braunwald E. Myocardial reperfusion, limitation of infarct size, reduction of left ventricular dysfunction, and improved survival: Should the paradigm be expanded? Circulation 1989;79:441–444. 93. Gruppo Italiano per lo Studio della Streptochinasi nell’Infarto Miocardico (GISSI). Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet 1986;1:397–402.
It is now evident that the atherosclerotic plaque and its cellular components represent an ideal substrate for thrombus formation. Thus, the term “atherothrombosis” appears fitting. Linking Events in Acute Coronary Syndromes 25 DEVELOPMENTAL ANATOMY AND CELLULAR BIOLOGY In experimental animals, focal sites of predilection for either spontaneous or dietaryinduced atherosclerosis can be determined reliably prior to plaque development. These areas are delineated by their in vivo uptake of the protein-binding azo dye Evans blue.
69. van der Berg EK, Schmitz JM, Benedict CR, Malloy CR, Willerson JT, Dehmer GJ. Transcardiac serotonin concentration is increased in selected patients with limiting angina complex coronary lesion morphology. Circulation 1989;79:116–124. 70. Becker RC, Tracy RP, Bovill EG, Mann KG, Ault K, for the TIMI-III Thrombosis and Anticoagulation Study Group. The clinical use of flow cytometry for assessing platelet activation in acute coronary syndromes. Coron Artery Dis 1994;5:339–345. 71. Lewis HD, Davis JW, Archibald DG, et al.