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Download Tumor-suppressing viruses, genes, and drugs : innovative by Hiroshi Maruta PDF

By Hiroshi Maruta

Tumor Suppressing Viruses, Genes, and medication profiles the hot iteration of melanoma remedies now in improvement. The booklet examines the cutting edge new techniques of viral, gene, and sign cures that promise to interchange or improve traditional tools corresponding to surgical procedure, radiation, and chemotherapy. The well timed details provided by way of this booklet could be of curiosity to a person concerned about advancing melanoma therapy past present scientific practices.

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Bartlett, D. , Alexander, H. , and Libutti, S. K. (1999). Sensitization of tumor necrosis factor ␣-resistant human melanoma by tumor-specific in vivo transfer of the gene encoding endothelial monocyte-activating polypeptide II using recombinant vaccinia virus. Cancer Res. 59, 4668 – 4674. Goodrum, F. , and Ornelles, D. A. (1997). The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle. J. Virol. 71, 548 – 561. , and Wimmer, E.

And Kufe, D. W. (2000). A phase I trial of 26 Hawkins and Kirn a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer. Clin. Cancer Res. 6, 1632 – 1638. Freytag, S. , Rogulski, K. , Paielli, D. , Gilbert, J. , and Kim, J. H. (1998). A novel threepronged approach to kill cancer cells selectively: Concomitant viral, double suicide gene, and radiotherapy [see comments]. Hum Gene Ther. 9, 1323 – 1333. , and Kyritsis, A. (2000). A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

Proc. Am. Soc. Clin. Oncol. 19, 724. , and Kirn, D. (2000c). Phase II trials with an E1B-55kD gene-deleted adenovirus in patients with recurrent head and neck carcinomas. Cancer Res. 60, 6359–6366. , and Babiss, L. E. (1991). Adenovirus E1A – p105(Rb) protein interactions play a direct role in the initiation but not the maintenance of the rodent cell transformed phenotype. Oncogene 6, 1031 – 1036. Norman, K, and Lee, P. (2000). Reovirus as a novel oncolytic agent. J. Clin. Invest. 105, 1035 – 1038.

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