By Priv.-Doz. Dr. med. H. Burkhard Dick, Dr. med. Oliver Schwenn (auth.)
This publication provides the elemental evidence of viscoelastic components. It introduces new, self-obtained info concerning viscoelastic rheological houses and describes the selective usages of viscoelastics in ophthalmic surgical procedure. a transparent and comprehensible presentation of viscoelastic physicochemical houses is emphasised to supply the training ophthalmic medical professional a reference advisor for the choice of an appropriate viscoelastic. The authors element the huge diversity of viscoelastic functions, the newest traits in visco-surgery, and describe the problems bobbing up from assorted surgical recommendations with definite viscoelastics. details at the construction of viscoelastic ingredients can also be incorporated. Tables and figures are used to record examine effects and facilitate knowing, whereas a topic index and an in depth bibliography offer effortless references. This ebook systematically provides uncomplicated wisdom and provides perception into the lastest purposes in surgical procedure in addition to the latest, proper findings within the box of viscoelastic research.
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Sample text
_. =!. Pseudoplasticity P, (quotient of the zero shear viscosity and viscosity at a shear rate of IOO/sec); sorted according to classes of substances and range of pseudoplasticity, in rising order; n=6) Table 7. lIsec and the viscosity at IOO/sec) and pseudoplasticity P, [quotient of the zero shear viscosity extrapolated using the Ellis-fit and the viscosity at a shear rate of IOO/sec); mean value (n = 6) 1 product Acrivi ce Adaloeel~ AMO Vitrax4' Amvisc Plus~ BioLon TN Coalel· Dispasan- (Ophthalin-) Oi pOl an Plus.
In the eye, high concentrations of sodium hyaluronate are present in the vitreous humor and in the connective tissue of the trabecular chamber angle. It is found in aqueous humor, although only in low concentrations, and covers the endothelium. , 1992). 4 mg/l (Laurent & Laurent, 1981), which covers the corneal endothelium in a thin, uninterrupted coat (Fig. 27), the function of which has not yet been clarified. The hyaluronic acid endothelial coating is presumably involved in Fig. 26. 27. Histologic cut through the human cornea after staining the bound hyaluronic acid with the help of the Avidinperoxidase-method: The surface of the corneal endothelium shows a thin but dense colour after streptomyces-hyaluronidase treatment to ensure the specificity of the staining method in the first place.
This inflammatory potential is best determined by an intravitreal injection into the owl monkey eye, followed by a slit lamp examination of the inflammatory process in the anterior chamber and vitreous body. This process has been established as a reproducible biological examination. Autodaving of sodium hyaluronate results in a significant depolymerization and change in viscosity (see below; Kim, 1987). Responsible for the relatively high expense associated with sodium hyaluronate solution are the considerable, technological demands for the production of a non-inflammatory compound, at a predetermined molecular weight.