By Albrecht Lindemann (auth.), Roland Mertelsmann (eds.)
Contents: creation and evaluate Lymphopoietic development elements: Pathophysiology of T-Cell Mediated surprise caused via Bacterial Superantigens - typical Killer Cells and Interleukin-2-Activated Killer Cells - TumourImmunogenicity precipitated by means of Exogenous Interleukins - Cytokine Gene remedy of melanoma - research of T-Cell Receptor Variability in Tumour Infiltrating Lymphocytes - scientific reports with Interleukin-2: an summary - medical Trials with neighborhood management of Lymphopoietic development elements - medical Trials with Interlaukin-2. The Rome adventure. Haematopoietic development elements: Lymphohaematopoietic development issue Use in Lung melanoma sufferers - medical Trials with Haematopoietic development elements and Peripheral Blood Stem Cells
Read Online or Download Lymphohaematopoietic Growth Factors in Cancer Therapy II PDF
Similar cancer books
Cancer Cell Culture: Methods and Protocols
With many fresh advances, melanoma mobilephone tradition study is extra very important than ever prior to. This well timed version of melanoma mobilephone tradition: equipment and Protocols covers the fundamental thoughts of melanoma mobilephone biology and tradition whereas increasing upon the hot shift in cellphone tradition tools from the new release of recent phone strains to using fundamental cells.
Die tierische Zelle in Zellkultur
Die ersten erfolgreichen Versuche zur Züchtung tierischer Zellen außerhalb des Organismus reichen zurück in den Beginn unseres Jahrhunderts. 1907 gelang HARRI SON durch Explantation von Gewebsstücken aus Froschembryonen der Nachweis, daß in der Embryonalentwicklung die Neuriten als Fortsätze der Nervenzelle ohne Be teiligung anderer Zellen gebildet werden, und daß damit eine spezifische celluläre Funktion auch außerhalb des Gesamtorganismus zu beobachten ist [310,311].
Port-Site and Wound Recurrences in Cancer Surgery: Incidence - Pathogenesis - Prevention
Prior to now nine years, reviews of 'port-site' deposits following laparoscopic surgical procedure for malignancy, specially laparoscopic resection of colonic melanoma, have solid a shadow at the knowledge of the laparoscopic method within the surgical guy agement in sufferers with melanoma. these stories of port-site deposits, a few ninety situations stated within the literature as much as 1999, have opened a 'can of worms' and highlighted the shortage of our wisdom on melanoma telephone migration from good tu mors and the criteria that underlie their profitable implantation in surgical wounds either within the presence and shortage of a good strain pneumoperito neum.
- Skin Cancer after Organ Transplantation
- Colon Cancer Prevention: Dietary Modulation of Cellular and Molecular Mechanisms
- Dietary Fat and Cancer: Genetic and Molecular Interactions
- Cancer Clinical Trials: Proactive Strategies
Additional info for Lymphohaematopoietic Growth Factors in Cancer Therapy II
Example text
Cancer Res 1987 (47):6353-6362 47 Schwarz RE, Iwatsuki S, Herberman RB et al: Lymphokine-activated killer cell activity in patients 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 with primary and metastatic malignant liver tumors. Hepatology 1989 (10):221-227 Whiteside TL, Heo OS, Takagi S et al: Characterization of novel antitumor effector cells in long-term cultures of human tumor-infiltrating lymphocytes. Transplant Proc 1988 (20):347-350 Hata K, Zhang XR, Iwatsuki S, VanThiel DH, Herberman RB, Whiteside TL: Isolation, phenotyping, and functional analysis of lymphocytes from human liver.
Rosenberg reproduced these findings with the murine fibrosarcoma MCA 205 and MCA 102. Despite many attempts, they were unable to generate in vivo immunity against the unmodified tumour. Then, using retroviral vectors, the IL-2 gene was introduced into these tumour cells. The secretion of IL-2 by the tumour cells abrogated their ability to generate subcutaneous tumours and could also cause the reduction in growth of nontransduced tumour at the same site. The immunologic nature of this response was demonstrated by the fact that IL-2 secreting tumours could grow in mice that were depleted of CD8 cells (S.
Int J Cancer 1976 (18):593-604 Steinhauer EH, Doyle AT, Reed J, Kadish A: Effective natural cytotoxicity in patients with cancer: Normal number of effector cells but decreased recycling capacity in patients with advanced disease. J Immunol 1982 (129):22552259 Tursz T, Dokhelar M, Lipinski M et al: Low natural killer cell activity in patients with malignant lymphoma. Cancer 1982 (50):2333-2335 Cunningham-Rundles S, Philippa DA, Braun DW et al: Natural cytotoxicity of peripheral blood lymphocytes and regional lymph node cells in breast cancer in women.